KMID : 0903519980410020197
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology 1998 Volume.41 No. 2 p.197 ~ p.200
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lsolation of Biologically Active Compounds from the Flower Petals of Carthamus tinctorius L.
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Abstract
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The MeOH extracts obtained from the flower petals of Carthamus tinctorius were solvent-fractionated with EtOAc, n-BuOH, and H©üO, successively. From the n-BuOH exact 2 flavonoid compounds were isolated through the repeated silica gel column chromatographies. From not only the results of physico-chemical data including HMBC but also the adaptation of acid hydrolysis, the chemical structures of the compounds were determined as 3-¥Ï-[¥â-D-glucopyranosyl (1¡æ2) ¥â-D-glucopyranosyl] kaempferol and 3-¥Ï-[¥á-L-rhamnopyranosyl (1¡æ6) ¥â-D-glucopyranosyl] kaempferol. The compounds exhibited IC_(50) values in Grab2-Shc activity to be 43 and 47 §¶/§¢, respectively.
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